5 Simple Techniques For oxycontin

5 Simple Techniques For oxycontin

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Appraise for indications of opioid withdrawal. If a CYP3A4 inducer is discontinued, look at OXYCONTIN dosage reduction and Consider patients at frequent intervals for signs of respiratory despair and sedation.

So as to keep away from creating withdrawal signs or symptoms, instruct individuals never to discontinue OXYCONTIN with no initial discussing a tapering program Along with the prescriber [see DOSAGE AND ADMINISTRATION].

OxyContin really should only be utilized by Individuals who have currently attempted and tolerated shorter-acting varieties of oxycodone and that have significant soreness necessitating spherical-the-clock agony aid. OxyContin really should not be taken on an 'as needed' or 'as essential' basis.

Expecting or intending to grow to be Expecting. Usage of OXYCONTIN for an extended time frame during pregnancy might cause withdrawal symptoms in the new child toddler that would be life-threatening if not identified and treated.

You will find a marriage amongst raising oxycodone plasma concentration and raising frequency of dose-similar opioid adverse reactions including nausea, vomiting, CNS results, and respiratory despair.

In sufferers getting opioids for an prolonged length of time at significant doses, ensure that a multimodal method of suffering administration, like psychological health support (if needed), is in place just before initiating an opioid analgesic taper [see DOSAGE AND ADMINISTRATION and WARNINGS AND PRECAUTIONS].

Advise patients and caregivers not to increase opioid dosage without the need of very first consulting here a clinician. Suggest patients to seek professional medical focus should they working experience signs or symptoms of hyperalgesia, which includes worsening discomfort, elevated sensitivity to agony, or new ache [see WARNINGS AND Safety measures and ADVERSE REACTIONS].

In the event you pass up a dose, skip the missed dose. Acquire your up coming dose at the normal time. Usually do not double the dose to capture up.

The use of OXYCONTIN isn't encouraged for people getting MAOIs or within 14 times of halting such remedy.

Your health care provider may perhaps suggest you get naloxone (a medication to reverse an opioid overdose) and maintain it along with you all of the time. A person caring in your case can provide the naloxone in the event you end respiratory or Will not wake up.

OXYCONTIN really should be prescribed only by healthcare experts who're proficient about the get more info use of prolonged-launch/lengthy-performing opioids and how to mitigate website the affiliated risks.

Never share opioid medication with A further human being, In particular somebody having a historical past of drug abuse or dependancy. MISUSE Could cause ADDICTION, OVERDOSE, OR Loss of life. Maintain the medication in a place where by Other people are not able to reach it. Promoting or making a gift of opioid medication is against the law.

Oxycodone is extensively metabolized by multiple metabolic pathways to supply noroxycodone, oxymorphone and noroxymorphone, which might be subsequently glucuronidated. Noroxycodone and noroxymorphone are the main circulating metabolites.

Instruct people to not share OXYCONTIN with Many others and also to consider steps to protect OXYCONTIN from theft or misuse.